Från nerv till pillerFrån nerv till pillerTid: Fredagen den 27 april kl 09:00-17:30
Plats: Aulan, Skånes universitetssjukhus, Lund
Deltagande och förtäring är kostnadsfritt!
Bindande anmälan senast den 7 april 2012 till Kgl. Fysiografiska Sällskapets kansli: 046- 13 25 28, kansli@fysiografen.se
För snart 50 år sedan publicerades den första rapporten om en ny och revolutionerande metod för histokemisk påvisning av katekolaminer och serotonin i vävnader. Metodens upphovsmän var Bengt Falck och Nils-Åke Hillarp, som båda var verksamma vid Histologiska institutionen i Lund. Falck-Hillarp metoden har sedan dess fått omvälvande konsekvenser inom vitt skilda medicinska områden Relativt snabbt kunde resultaten från neurobiologisk och endokrinologisk grundforskning omsättas i praktisk klinisk sjukvård. Med anledning av det stundande 50-årsjubileet vill forskare från Lund, Göteborg och Stockholm beskriva landvinningarna i spåren av Falck-Hillarp-metoden.
Forskarna kommer bland annat att föreläsa om:
Organisationskommitté:
Lunds Universitet: Per Alm, Anders Björklund, Berndt Ehinger, Rolf Håkanson, Olle Lindvall, Nils-Otto Sjöberg och Frank Sundler
Göteborgs Universitet: Annica Dahlström
Karolinska Institutet: Kjell Fuxe, Tomas Hökfelt och Lars Olson
In English
The "Aula" lecture Hall, University Hospital at Lund
Supported by the Royal Physiographic Society, the Faculty of Medicine at Lund and the Lund University.
The first report of a fluorescence microscopic technique to demonstrate catechol amines and serotonin in neurons and nerve fibers appeared 50 years ago. The method, which became known as the Falck-Hillarp-method, made it possible to visualize monoamine-containing neurons and nerve fibers. Later, it turned out that that the technique could also be used to demonstrate peptide-hormone-containing endocrine cells throughout the body. The method was invented and perfected by Bengt Falck and Nils-Åke Hillarp, working in close collaboration with Arvid Carlsson, who developed fluorometric methods to measure catechol amines and serotonin in tissue extracts. The work was initiated in Lund, and it was continued by Bengt Falck at Lund University, by Nils-Åke Hillarp at the Karolinska Institute in Stockholm, and in Gothenburg where Arvid Carlsson was appointed professor and chairman of the Department of Pharmacology.
The three pioneers gathered around them groups of young and ambitious disciples who during the following decades made Swedish neurobiology internationally known and highly respected. The combination of histochemical and pharmacologial methods was unique and produced results and insights that improved our understanding of a number of clinically important issues, and made it possible to introduce new and effective treatments of a number of neurological and neuropsychiatric disorders.
The 50-year anniversary of the introduction of the Falck-Hillarp-method will be celebrated by a symposium in Lund on April 27, 2012, entitled “From Nerves to Pills”. Speakers in this symposium will document and describe some of the most important achievements in neurobiology and endocrinology that have their origin in the new knowledge gained as a result of the revolution in histochemistry represented by the Falck-Hillarp method. Many of these advances have been successfully translated into clinically useful drugs and treatments.
Organisation committee:
Lund University: Per Alm, Anders Björklund, Berndt Ehinger, Rolf Håkanson, Olle Lindvall, Nils-Otto Sjöberg, and Frank Sundler
Göteborg University: Annica Dahlström
Karolinska Institute: Kjell Fuxe, Tomas Hökfelt, and Lars Olson